先端医療情報技術研究部について

研究内容

• 医療従事者コミュニケーションアプリケーション
• 遠隔医療/費用対効果
• 健常サポートアプリケーション
• 緊急時、食、大人・子供緊急マニュアル
• 介護アプリケーション
• ビックデータ解析（AI）
• IoT開発（スマホで血圧計等）
• 携帯電波影響
• 医療機器開発（ステント等）
• ICT医療（医療最適化・評価やICTを用いた治療）
• ICT栄養学
• ロボットを用いた医学的影響
• PHR（Personal Health Records）
• ICTを用いた地域連携
• 医工連携（流体力学・構造解析）

髙尾洋之の紹介

研究業績（List of Previous Publications and Researches）

1. Tominari S, Morita A, Ishibashi T, Yamazaki T, Takao H, Murayama Y, Sonobe M, Yonekura M, Saito N, Shiokawa Y, Date I, Tominaga T, Nozaki K, Houkin K, Miyamoto S, Kirino T, Hashi K, Nakayama T; Unruptured Cerebral Aneurysm Study Japan Investigators, “Prediction model for 3-year rupture risk of unruptured cerebral aneurysms in Japanese patients”, Ann Neurol., 2015 Jun;77(6):1050-9. Fujimoto M, Salamon N, Takemoto K, Takao H, Song L, Tateshima S, Viñuela F, “Correlation of clot imaging with endovascular recanalization in internal carotid artery terminus occlusion”, J Neurointerv Surg. 2015 Feb;7(2):131-4.
2. Fujimoto M, Salamon N, Takemoto K, Takao H, Song L, Tateshima S, Viñuela F, “Correlation of clot imaging with endovascular recanalization in internal carotid artery terminus occlusion”, J Neurointerv Surg. 2015 Feb;7(2):131-4.
3. Suzuki T, Takao H, Suzuki T, Kambayashi Y, Watanabe M, Shinohara S, Fujiwara H, Nakazato S, Watanabe M, Dahmani C, Yamamoto M, Fujii Y, Murayama Y, “Fluid structure interaction analysis reveals facial nerve palsy caused by vertebral-posterior inferior cerebellar artery aneurysm”, Comput Biol Med. 2015 Nov 1;66:263-8.
4. Hishikawa T, Date I, Tokunaga K, Tominari S, Nozaki K, Shiokawa Y, Houkin K, Murayama Y, Ishibashi T, Takao H, Kimura T, Nakayama T, Morita A, “Risk of rupture of unruptured cerebral aneurysms in elderly patients, For UCAS Japan and UCAS II Investigators”, Neurology. 2015 Nov 24;85(21):1879-85.
5. Suzuki T, Takao H, Fujimura S, Dahmani C, Ishibashi T, Mamori H, Fukushima N, Murayama Y, Yamamoto M. Relationships between geometrical parameters and mechanical properties for a helical braided flow diverter stent. Technol Health Care. 2016. [Accepted]
6. Misaki K, Takao H, Suzuki T, Nishimura K, Kan I, Yuki I, Ishibashi T, Yamamoto M, Murayama Y. Estimated pretreatment hemodynamic prognostic factors of aneurysm recurrence after endovascular embolization. Technol Health Care. 2016. [Accepted]
7. Yuki I, Kambayashi Y, Ikemura A, Abe Y, Kan I, Mohamed A, Dahmani C, Suzuki T, Ishibashi T, Takao H, Urashima M, Murayama Y, “High-Resolution C-Arm CT and Metal Artifact Reduction Software: A Novel Imaging Modality for Analyzing Aneurysms Treated with Stent-Assisted Coil Embolization”, AJNR Am J Neuroradiol. 2016 Feb;37(2):317-23.
8. Murayama Y, Takao H, Ishibashi T, Saguchi T, Ebara M, Yuki I, Arakawa H, Irie K, Urashima M, Molyneux AJ, “Risk Analysis of Unruptured Intracranial Aneurysms: Prospective 10-Year Cohort Study”,　 Stroke. 2016 Feb;47(2):365-71.
9. Kambayashi Y, Takao H, Shinohara K, Suzuki T, Takayama S, Fujimura S, Masuda S, Watanabe M, Suzuki T, Dahmani C, Ishibashi T, Yamamoto M, Murayama Y. Computational fluid dynamics analysis of tandem carotid artery stenoses: Investigation of neurological complications after carotid artery stenting. Technol Health Care. 2016 Sep; 24(5):673-9.
10. Suzuki T, Takao H, Suzuki T, Suzuki T, Masuda S, Dahmani C, Watanabe M, Mamori H, Ishibashi T, Yamamoto H, Yamamoto M, Murayama Y. Variability of hemodynamic parameters using the common viscosity assumption in a computational fluid dynamics analysis of intracranial aneurysms. Technol Health Care. 2016 Sep. [Epub ahead of print]
11. Suzuki T, Takao H, Fujimura S, Dahmani C, Ishibashi T, Mamori H, Fukushima N, Yamamoto M, Murayama Y. Selection of helical braided flow diverter stents based on hemodynamic performance and mechanical properties. J Neurointerv Surg. 2016 Sep. [Epub ahead of print]
12. Suzuki T, Takao H, Suzuki T, Kambayashi Y, Watanabe M, Sakamoto H, Kan I, Nishimura K, Kaku S, Ishibashi T, Ikeuchi S, Yamamoto M, Fujii Y, Murayama Y. “Determining the presence of thin-walled regions at high-pressure areas in unruptured cerebral aneurysms by using computational fluid dynamics.” Neurosurgery. 2016 Oct;79(4):589-95.
13. Ishibashi T, Takao H, Suzuki T, Yuki I, Kaku S, Kan I, Nishimura K, Suzuki T, Watanabe M, Karagiozov K, Murayama Y. Tailor-made shaping of microcatheters using three-dimensional printed vessel models for endovascular coil embolization. Comput Biol Med. 2016 Oct;77:59-63.
14. Fujimura S, Takao H, Suzuki T, Dahmani C, Ishibashi T, Mamori H, Yamamoto M, Murayama Y. A new combined parameter predicts re-treatment for coil-embolized aneurysms: a computational fluid dynamics multivariable analysis study. J Neurointerv Surg. 2017 Dec. [Epub ahead of print]
15. Fujimura S, Takao H, Suzuki T, Dahmani C, Ishibashi T, Mamori H, Yamamoto M, Murayama Y. Hemodynamics and coil distribution with changing coil stiffness and length in intracranial aneurysms. J Neurointerv Surg. 2017 Dec. [Epub ahead of print]
16. Berg P, Voß S, Saalfeld S, Janiga G, Bergersen AW, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A, Cancelliere NM, Steinman DA, Pereira VM, Chiu TL, Tsang ACO, Chung BJ, Cebral JR, Cito S, Pallarès J, Copelli G, Csippa B, Paál G, Fujimura S, Takao H, Hodis S, Hille G, Karmonik C2 Elias S, Kellermann K, Khan MO, Marsden AL, Morales HG, Piskin S, Finol EA, Pravdivtseva M, Rajabzadeh-Oghaz H, Paliwal N, Meng H, Seshadhri S, Howard M, Shojima M, Sugiyama SI, Niizuma K, Sindeev S, Frolov S, Wagner T, Brawanski A, Qian Y, Wu YA, Carlson KD, Dragomir-Daescu D, Beuing O. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation. Cardiovascular Engineering and Technology. 2018 Dec;9(4):565-581
17. Tanaka K, Takao H, Suzuki T, Suzuki T, Fujimura S, Uchiyama Y, Ono H, Otani K, Ishibashi T, Yamamoto M, Murayama Y. A Parameter to Identify Thin-walled Regions in Aneurysms by CFD. Journal of Neuroendovascular Therapy. 2019 June;13(6):241-249.
18. Detmer FJ, Hadad S, Chung BJ, Mut F, Slawski M, Juchler N, Kurtcuoglu V, Hirsch S, Bijlenga P, Uchiyama Y, Fujimura S, Yamamoto M, Murayama Y, Takao H, Koivisto T, Frösen J, Cebral JR. Extending statistical learning for aneurysm rupture assessment to Finnish and Japanese populations using morphology, hemodynamics, and patient characteristics. Neurosurg Focus. 2019 July 1;47(1):E12.
19. Murayama Y, Fujimura S, Suzuki T, Takao H. Computational fluid dynamics as a risk assessment tool for aneurysm rupture. Neurosurg Focus. 2019 July 1;47(1):E12.
20. Berg P, Voß S, Janiga G, Saalfeld S, Bergersen AW, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A, Chiu TL, Tsang ACO, Copelli G, Csippa B, Paál G, Závodszky G, Detmer FJ, Chung BJ, Cebral JR, Fujimura S, Takao H, Karmonik C, Elias S, Cancelliere NM, Najafi M, Steinman DA, Pereira VM, Piskin S, Finol EA, Pravdivtseva M, Velvaluri P, Rajabzadeh-Oghaz H, Paliwal N, Meng H, Seshadhri S, Venguru S, Shojima M, Sindeev S, Frolov S, Qian Y, Wu YA, Carlson KD, Kallmes DF, Dragomir-Daescu D, Beuing O. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)-phase II: rupture risk assessment. Int J Comput Assist Radiol Surg. 2019 Oct;14(10):1795-1804.
21. Nishimura K, Otani K, Mohamed A, Dahmani C, Ishibashi T, Yuki I, Kaku S, Takao H, Murayama Y. Accuracy of Length of Virtual Stents in Treatment of Intracranial Wide-Necked Aneurysms. Cardiovasc Intervent Radiol. 2019 Aug;42(8):1168-1174. doi: 10.1007/s00270-019-02230-9.
22. Nambu I, Misaki K, Uchiyama N, Mohri M, Suzuki T, Takao H, Murayama Y, Futami K, Kawamura T, Inoguchi Y, Matsuzawa T, Nakada M. High Pressure in Virtual Postcoiling Model is a Predictor of Internal Carotid Artery Aneurysm Recurrence After Coiling. Neurosurgery. 2019 Mar 1;84(3):607-615. doi: 10.1093/neuros/nyy073.
23. Suzuki T, Takao H, Rapaka S, Fujimura S, Nita CI, Uchiyama Y, Tanaka K, Ohno H, Otani K, Dahmani C, Mihalef V, Sharma P, Mohamed A, Redel T, Ishibashi T, Yamamoto M, Murayama Y. Rupture risk of small unruptured intracranial aneurysms in Japanese adults. Stroke. 2020 Feb;51(2):641-643.
24. Shiozaki S, Otani T, Fujimura S, Takao H, Wada S. Computational Modeling of Braided Stent Deployment for Interpreting the Mechanism of Stent Flattening. 1. Int J Numer Method Biomed Eng. Int J Numer Method Biomed Eng. 2020 Mar 25. doi: 10.1002/cnm.3335. Online ahead of print.
25. Nita CI, Suzuki T, Itu LM, Mihalef V, Takao H, Murayama Y, Sharma P, Redel T, Rapaka S. An Automated Workflow for Hemodynamic Computations in Cerebral Aneurysms. Comput Math Methods Med. 2020 Jun 17;2020:5954617. doi: 10.1155/2020/5954617. PMID: 32655681; PMCID: PMC7317611.
26. Sakai K, Komatsu T, Iguchi Y, Takao H, Ishibashi T, Murayama Y. Reliability of Smartphone for Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores in Acute Ischemic Stroke Patients: Diagnostic Test Accuracy Study. J Med Internet Res. 2020 Jun 9;22(6):e15893. doi: 10.2196/15893.
27. Suzuki T, Takao H, Suzuki T, Hataoka S, Kodama T, Aoki K, Otani K, Ishibashi T, Yamamoto H, Murayama Y, Yamamoto M. Proposal of hematocrit-based non-ewtonian viscosity model and its significance in intracranial aneurysm blood flow simulation. Journal of Non-Newtonian Fluid Mechanics. 2021 April;290 104511. doi: 10.1016/j.jnnfm.2021.104511
28. Sakai K, Sato T, Komatsu T, Mitsumura H, Iguchi Y, Ishibashi T, Murayama Y, Takeshita K, Takao H. Communication-type smartphone application can contribute to reducing elapsed time to reperfusion therapy. Neurol Sci. 2021 Feb 26;1-6. doi: 10.1007/s10072-021-05132-2. Online ahead of print.
29. Takao H, Sakai K, Mitsumura H, Komatsu T, Yuki I, Takeshita K, Sakuta K, Ishibashi T, Sakano T, Yeh Y, Karagiozov K, Fisher M, Iguchi Y, Murayama Y. A Smartphone Application as a Telemedicine Tool for Stroke Care Management. Neurol Med Chir (Tokyo). 2021 Mar 12. doi: 10.2176/nmc.oa.2020-0302. Online ahead of print.
30. Takeshita K, Takao H, Sakai K, Iguchi Y, Murayama Y, Study on factors related to hospitalization period of acute cerebral infarction using NDB sampling data set. Japanese Journal of Stroke. 2021 Jan. doi: 10.3995/jstroke.10849. Online ahead of print.
31. 武田聡, 竹下康平, 高尾洋之, 情報技術を用いた救急医療・災害医療をつなぐ・支える取り組み. 計測と制御. 2020 April 10;59(4):263-268.
32. Sakano T, Urashima M, Takao H, Takeshita K, Kobashi H, Fujiwara T, “Differential Kinetics of Cycle Threshold Values during Admission by Symptoms among Patients with Mild COVID-19: A Prospective Cohort Study”, Int J Environ Res Public Health. 2021 Aug 2;18(15):8181.
33. Fujimura S, Tanaka K, Takao H, Okudaira T, Koseki H, Hasebe A, Suzuki T, Uchiyama Y, Ishibashi T, Otani K, Karagiozov K, Fukudome K, Hayakawa M, Yamamoto M, Murayama Y, “Computational Fluid Dynamic Analysis of the Initiation of Cerebral Aneurysms”, J Neurosurg. 2021 [Accepted]
34. Ishii T, Fujimura S, Takao H, Uchiyama Y, Okudaira T, Ishibashi T, Otani K, Karagiozov K, Fukudome K, Yamamoto M, Murayama Y, “Hemodynamic and Morphological Factors Related to Coil Compaction in Basilar Artery Tip Aneurysms”, World Neurosurg. 2021 [Accepted]
35. Takao H, Watanabe D, Tani S, Ohashi H, Ishibashi T, Takeshita K, Murakami S, Nishimoto T, Yuge K, Karagiozov K, Abe T, Murayama Y, ”Use of a Simulation Model to Investigate the Mechanisms of Sports-related Head Injuries”, Neurol Med Chir (Tokyo). 2021[Online ahead of print]
36. ”Difference in Rupture Risk Between Familial and Sporadic Intracranial Aneurysms: An Individual Patient Data Meta-analysis”, Neurology. 2021[Accepted]
37. Uchiyama Y, Fujimura S, Takao H, Suzuki T, Hayakawa M, Ishibashi T, Karagiozov K, Fukudome K, Murayama Y, Yamamoto M, ” Hemodynamic Investigation of the Effectiveness of a Two Overlapping Flow Diverter Configuration for Cerebral Aneurysm Treatment”, Bioengineering (Basel). 2021[Accepted]

書籍（Book）

• 東京慈恵会医科大学 先端医療情報技術研究講座 (著)
  「スマホで始まる未来の医療 医療+ICTの最前線」
  2016/6/28 第一版第一刷
  日経BP社
  
  東京慈恵医科大学は、iPhoneを病院内に3400台導入し、スマートフォンで利用できるナースコールシステムの導入や院内Wi-Fi網の充実など数多くの改革を実施しました。本書では、こうした大学での取り組みをはじめ、これからの医療に欠かせない「スマホ」を活用したICT医療の事例を多数紹介。たくさんのソリューションから医療の将来像が垣間見えていきます。
• 山本 誠 (監修), 根本 繁 (編集), 髙尾 洋之 (編集)
  「基礎からよくわかる 実践的CFD(数値流体力学)入門 脳血管編: 今すぐ始められる! 研究用CFDフリーソフト付き!」
  2017/4/5 第一版第一刷
  株式会社メディカ出版
  
  脳動脈瘤等の研究に用いられ注目を集めているCFD（数値流体力学）について、臨床現場で働く医師と理工系の研究者がともに作り上げた本邦初の本格的な入門書。豊富なイラストに加えわかりやすい文章とポイント解説で、医師にも理工系研究者にも親しみやすい内容になっています。本書編集陣が開発したCFDフリーソフト付きで、今すぐCFDを始められます。
• 髙尾 洋之 (著)
  「鉄腕アトムのような医師 AIとスマホが変える日本の医療」
  2017/10/17 第一版第一刷
  日経BP社
  
  人工知能（AI）やICT、IoT、ロボットといったテクノロジーは、医療の未来をどのように変えていくのでしょうか。本書では、これらICT医療の最新事例を紹介しつつ、最近注目されはじめた「遠隔医療」や「パーソナルヘルスレコード（PHR）」に関する日本の医療制度の状況についても詳細に説明しています。日本の未来の医療を考えるきっかけにしていただきたい1冊です。